Advance Journal of Virology, Epidemic and Pandemic Diseases

The principal disconnection of chikungunya infection from non-human primates in Malaysia


R. M. Apandi, K. F. Nazni and D O. Noor

Chikungunya is a mosquito borne disease caused by chikungunya virus (CHIKV) . The virus is
transmitted to human by Aedes genus mosquitoes. Transmission cycles of CHIKV can be man -
mosquito - man (urban cycle) or animal - mosquito - man (sylvatic cycle). Sylvatic transmission cycle of
CHIKV has been described in Africa and may play a role in re-emergence of CHIKV infection. In
Malaysia, CHIKV- neutralizing antibodies have been detected among wild monkeys in mid 1960s but so
far CHIKV has never been isolated in monkeys.


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