Background: Multidrug-Resistant (MDR) bacteria cause a serious threat to all fields of bioscience because it may result in treatment failure which might have severe consequences, especially in case of critical or special patients. The development of new antibacterial agents cropped up to be a complex process.
Main body: One of the most important aspects of modern field research is nanotechnology, it deals with synthesis, design and manipulation of particles structures ranging from approximately 1-100 nm. Nanoparticles (NPs) are of great importance in areas like health care, cosmetics, food and feed, environmental health etc. Nanoparticles matrix properties and constituent materials can be used to categorize them into inorganic and organic nanosystems. Techniques use within the synthesis of NPs includes; chemical, physical, chemistry, and biological methods, every methodology has its advantages and disadvantages with common issues of value, quantifiability and uniform particle size. Sir Alexander Fleming, a noble winner aforesaid that “There is perhaps no therapy drug to that in appropriate circumstances the bacteria can't react by in a way deed fastness.” thus, there's high chance that the organism can also become resistance to newly developed medication at later stage.
Conclusion: To this end NPs are considered to be good antibacterial agents and may overcome the barrier of MDR owing to their ability to anchor to the bacterial cell wall, multifunctional mechanisms to intervene normal cell functionality and subsequently penetrate it, thereby causing structural changes in the cell membrane permeability leading to cell death.HTML PDF
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